Apr 8, 2018 - 12:23 AM
Most mountain passes will be closed.
I can think of only one 'highland' option
Normally you would be able to go Annecy - Chamonix - Martigny in winter but the Col de la Forclaz is closed by rockfall which happened during the very bad weather a few months ago.
The only option therefore would be Annecy - Genève - Lausanne - Sion - Brig - Simplon Pass (kept open all winter) Domodossola, Italian road number SS33 to Gravellona then SS34 to Intra and along Lake Maggiore (some sections right by the lake) - Locarno - Lugano (around 7 hours but pretty scenic all told)