Sep 22, 2017 - 7:08 AM
in reply to monicatravel
Depending on your budget, the car rental is quite an expensive option.
Now for the trains: I'd consider the Wengen to Interlaken Ost one leg of the journey, even if you have to change 1 time already (Lauterbrunnen). Nothing to do there, it's the Swiss regional based train network.
Once arrived in Interlaken Ost, the best option (in fact, the fastest) is to take the IC towards Basel, change at Spiez onto the EC towards Milano Centrale, then take the RE_8 (italian regional train) towards Sondrio and get off it at Varenna (another 2 changes, as Rockoyster pointed above). So this is the "only four train changes" option. And the fastest one, at the same time. From Varenna, here's the ferry timetable to Bellagio:
www.navigazionelaghi.i t/c_download/NLC_TRAGH ETTO%20E2017.pdf
They're one each 40 minutes or so, up to 22.50 late evening, so no stress there.
Any other choice, you have to switch at least 5-6 times, be it through Zuerich/Luzern or the tunnels to Domodossola. Up to you to choose the best option that suits the whole family.
Have a safe trip.