Sep 21, 2013 - 3:07 AM
Hi lisalyl78, welcome to MySwissAlps,
Switzerland's road network is of good quality. Whether driving would be easy for you depends on when you're traveling (in Winter there can be snow/slippery roads) and what you're used to at home. Parking can be difficult and expensive in larger towns like Interlaken and Lucerne, unless you have free parking included with the hotels. Public transport is perfect and easy to use. A visit to the Jungfraujoch by car would mean that you park in Lauterbrunnen or Grindelwald and continue by train. It makes sense to just take the train directly from Interlaken. You can walk from your hotel to either the Interlaken West or Ost rail station. There are direct trains from Interlaken to Basel (about 2 hours). A 20 minute bus ride takes you to the airport. Details are in the timetable
. Bern is on the way to Basel, so you can spend a couple of hours there.
Fares to the Jungfraujoch are here
. You'd best look into the rail passes
to get a discount on that excursion and the other ones you may have planned. Hotels near the rail stations can be found here